Technologies

Accelerating the Development and Commercialization of Revolutionary Therapeutics.

Pluristyx Technologies

Pluristyx has curated a portfolio of innovative technologies aimed at enhancing and enabling allogenic cell therapies. Our proprietary techniques have been designed by an executive team with over 50 years of expertise and industry experience aiming to reduce issues commonly faced by the cell therapy field.

The Pluripotent Stem Cell (iPSC) Solution has a lot of promising qualities and potential for treating currently incurable diseases. Pluristyx is ready to enable, Tomorrow’s Cell Therapies Today®.

Patent protected technologies

With our enlarged portfolio of unique non-modified and genetically engineered iPSC-based technologies, we can assist you at any stage in establishing proof of concept through to commercialization.  

One Cell For All

Offering an array of gene editing technologies resulting in unparalleled functional control of commercial products.

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FailSafe®

A reliable safeguard against transplants becoming tumorigenic – any unwanted cells can be eliminated with a simple source of drug treatment
Our FailSafe® technology offers an ideal solution: all transplanted cells and their derivatives that are proliferating can easily be eliminated with our “kill switch” safeguard by treating the patient with a drug instead of surgery.
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Cellular Reprogramming

Proprietary footprint-free RNA reprogramming method to generate induced Pluripotent Stem Cells (iPSC)
Pluristyx’s iPSCs are produced using mRNA, engineered to increase the level of protein/transcription factor expression and facilitate the reprogramming of somatic cells into induced pluripotent stem cells. Pluristyx’s iPSC have been shown to differentiate into a wide range of cell types.
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iACT Stealth Cells™

A groundbreaking technology that enables allograft transplantation without the need for systemic immune suppression
Our groundbreaking iACT technology with immune-modulatory genes allows the acceptance of allografts without the need for systemic immune suppression. Equipping pluripotent stem cells with this technology will allow the same cell line to be used for differentiation and ultimately transplantation into any individual.
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Cryopreservation

End-to-end cryopreservation services to ensure successful patient administration on day one.
Pluristyx employs industry experts who are skilled in the science and practice of cell therapy cryopreservation and can successfully design practical and economical cryopreservation methods individualized for specific cell therapy.
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REA Process & Licensing

Try Before You Buy
By offering the Research Evaluation Agreement you can gain access to our modified and non-modified cellular products for evaluation with our Try Before You Buy model. A smaller upfront payment limits your risk. Once you see the successful results, you can then enter into a license agreement with us panCELLa / Pluristyx.
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Simplifying Stem Cell Production

Pluristyx's portfolio of technologies makes the complicated induced pluripotent stem cell (iPSC) manufacturing simple by shortening the development lifecycle and removing the common barriers that block the translation of tomorrow’s cell therapies to the clinic. With full control of the upstream workflow, Pluristyx can help you select, license, genetically edit, and manufacture stem cells all under one roof.

Derivation
Gene Editing
Product
Banking
Expansion
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Our Products

Our Cellular Reprogramming technology provides clients access to high quality induced Pluripotent Stem cells (iPSC) that can be gene edited  to incorporate our proprietary platform gene edits FailSafe® and iACT Stealth Cells™.

These technologies combat the two of the major challenges identified in cell therapy: the risk of immune rejection when using cells from universal donors and concerns regarding the safety of gene-engineering. Our stem cells can be accessed for a low upfront cost to help select an appropriate line that will generate your downstream cellular product.

iPSC

Human pluripotent stem cells (iPSC) for use in R&D activities. Inquire for GMP grade cells suitable as a starting material in clinical applications. 

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Custom iPSC

Pluristyx can employ our mRNA reprogramming technology to generate custom hiPSC lines based on your specific requirements. Custom hiPSCs can be further modified to include our proprietary FailSafe® or iACT Stealth Cells™ technologies, as well as your custom genetic edits to generate the ideal starting material for your downstream product development and clinical manufacturing.

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Differentiated Cells
Pluristyx staff have decades of experience generating terminally differentiated cells using both off-the-shelf and proprietary protocols. Pluristyx welcomes the opportunity to discuss and fulfill your specific differentiation needs.
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iPSC

Human pluripotent stem cells (iPSC) for use in R&D activities. Inquire for GMP grade cells suitable as a starting material in clinical applications. 

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Custom iPSC

Pluristyx can employ our mRNA reprogramming technology to generate custom hiPSC lines based on your specific requirements. Custom hiPSCs can be further modified to include our proprietary FailSafe® or iACT Stealth Cells™ technologies, as well as your custom genetic edits to generate the ideal starting material for your downstream product development and clinical manufacturing.

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Differentiated Cells

Pluristyx staff have decades of experience generating terminally differentiated cells using both off-the-shelf and proprietary protocols. Pluristyx welcomes the opportunity to discuss and fulfill your specific differentiation needs.
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The panCELLa Platform:
The Solution

Developing the next generation of stem cell therapies is slow, hard, and expensive. Pluristyx offers a solution: the panCELLa platform. Through our platform, we take on the most difficult parts of your stem cell process, including CMC support, process and analytical development services, gene editing, and cell line development, to help you convert your concept into a clinical reality.

 

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70% reduction in development time
Proprietary technology with clear freedom to operate
Fastest path to clinic
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Solutions

Developing the next generation of stem cell therapies is slow, hard, and expensive. Pluristyx has the expertise needed to take on the most difficult parts of your stem cell process, including CMC support, process and analytical development services, gene editing, and cell line development, to help you convert your concept into a clinical reality.

View All Solutions
70% reduction in development time
Proprietary technology with clear freedom to operate
Fastest path to clinic
View All Solutions
See how we can help accelerate the development and commercialization of revoluntionary therapeutics

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