iACT Stealth Cells™
induced Allogeneic Cell Tolerance iPSC (iACT) Stealth Cells™
A groundbreaking technology that enables allograft transplantation without the need for systemic immune suppression
Our iACT Stealth Cell™ technology with immune-modulatory genes allows the acceptance of allografts without the need for systemic immune suppression. Equipping pluripotent stem cells with this technology will allow the same cell line to be used for differentiation and ultimately transplantation into any individual.
Cells equipped with iACT Stealth Cells™ avoid allograft immune recognition.
iACT Stealth Cells™ remove the need for patients to undergo immuno-suppressive treatments.
iACT Stealth Cells™ pave the way for universal “off-the-shelf” regenerative medicine therapies
Pluristyx has developed a genetic modification strategy that allows allogenic cells to evade immune rejection without the need for systemic immune suppression.
iACT Stealth Cell™ technology is based on a holistic view
All components of the immune response to an allograft are carefully addressed while placing special attention to the intricate interplay between each factor. Since disabling the immune system’s ability to recognize and eliminate “non-self” cells is inherently dangerous, it is imperative to combine such approaches with reliable safety approaches as our FailSafe® system.