PSXi013-A-2 FailSafe B2M/CIITA knockout R&D Vial

PSXi013-A-2 induced Pluripotent Stem Cells with FailSafe and B2M/CIITA knockout




PluriBankTM PSXi013-A-2 FailSafe® and B2M/CIITA knockout induced Human Pluripotent Stem Cells

Catalog Number:  PSXi013-A-2 CDK1-sFS BC

Cell number per vial:  >1 million at freeze


Product Summary

PSXi013-A-2 CDK1-sFS BC cells are fibroblast derived induced Pluripotent Stem Cells cryopreserved at greater than 1 million cells per vial with a >80% viable cell recovery when handled and thawed following the instructions for use.

The cells contain the FailSafe gene edit.  All cells and their derivatives that are proliferating can easily be eliminated with a “suicide switch” safeguard by treating the patient with a drug instead of surgery.

The cells are also B2M/CIITA homozygous knockouts.  All cells and their derivatives do not express HLA class I and HLA class II cell surface markers.


Format: Research Use Only; not for diagnostic or therapeutic purposes

Passage number:  <63

Donor Information: 56 year old, Healthy, Male, Caucasian

Karyotype:  46, XY; Normal by G-Band

Pluripotency Markers:   SSEA-4, OCT4, NANOG & SOX2 (>90%)

Gene Edits: FailSafe inserted in the CDK1 gene (suicide switch), B2M and CIITA gene knockouts (HLA class I and class II null)


Cell Source

PSXi013-A iPSCs were derived under current Good Tissue Practice (cGTP) and conform to Global Ethical Standards and Clinical Cell Regulations with complete donor history and testing information.


Cell Bank Manufacturing

Pluristyx iPSC cell bank vials are tested and confirmed to be free of adventitious agents, including mycoplasma, bacteria, yeast, fungi, and human virus.  The cells have been characterized with regards to karyotype, pluripotency, and have been Short Tandem Repeat (STR) fingerprinted to confirm cell line identity.



A one-time license payment for these Research Use Only (RUO) products is also required.  The fee depends on organization types.  An Acedemic organization has a license fee of $0.  A Bio-Pharma organization has a license fee of $5,000.  Please contact us for arrangements with the license.

These cells are for Research Use Only (RUO) and shall not be developed for diagnostic, therapeutic, or commercial use.  Please enquire with Pluristyx for GMP grade vials that may be used for clinical or commercial use.

Additional Information

SKU PSXi013-A-1-1 Category
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